The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis. The discovery of insulin has saved the lives ...

Insulin is a hormone that helps shuttle sugar from your blood into the cells in your body. People with type 1 diabetes or advanced type 2 diabetes need to administer insulin to keep their blood sugar ...

Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...

In December 1921, 14-year-old Leonard Thompson was near death. The boy had diabetes and weighed just 65 pounds. After a month in Toronto General Hospital, he wasn’t improving, so his physicians turned ...

People with type I diabetes have to inject themselves multiple times a day with manufactured insulin to maintain healthy levels of the hormone, as their bodies do not naturally produce enough. The ...